Glucose control in young people with type 1 diabetes improved by intensive management

Young people with newly diagnosed type 1 diabetes who intensively manage their diabetes achieve better glucose control, latest evidence suggests.

New research has found that automated insulin delivery is beneficial for glucose control; however, it does not affect the decline in pancreatic C-peptide secretion.

During the randomised clinical trial, 113 youths aged between seven and 17 with newly diagnosed type 1 diabetes were analysed.

Each participant was randomly assigned to one of two diabetes management programmes, with half the group using an automated insulin delivery system and the other half using standard care techniques, such as continuous glucose monitoring.

The research team found that there was no significant difference in C-peptide levels measured during a mixed-meal tolerance test a year after diagnosis between the intensive management and standard care groups.

The findings state: “The mean time in the target range of 70 to 180 mg/dL, measured with continuous glucose monitoring, at 52 weeks was 78 per cent with intensive management, which included automated insulin delivery, compared with 64 per cent with standard care. One severe hypoglycaemia event and one diabetic ketoacidosis event occurred in each group.”

The study can be accessed here.