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Diabetes should be considered as ‘risk factor’ for COVID-19 rapid progression

By Editor
28th April 2020
Coronavirus, Research

Diabetes should be considered as a “risk factor” for the rapid progression and bad prognosis of COVID‐19, researchers have said.

A Chinese team have been looking at whether diabetes might influence the progression and prognosis of coronavirus by studying a total of 174 consecutive people with coronavirus.

All the participants had their demographic data, medical history, symptoms and signs, laboratory findings, chest computed tomography (CT) as well the treatment measures collected and analysed.

The research team said that people with diabetes who tested positive with COVID‐19, who did not have other comorbidities,  were at higher risk of severe pneumonia, release of tissue injury‐related enzymes, excessive uncontrolled inflammation responses and hypercoagulable state associated with dysregulation of glucose metabolism.

Rapid deterioration

Furthermore, serum levels of inflammation‐related biomarkers such as IL‐6, C‐reactive protein, serum ferritin and coagulation index, D‐dimer, were significantly higher (P < .01) among those with diabetes, compared with those without, suggesting that people with diabetes are more susceptible to an inflammatory storm eventually leading to rapid deterioration of COVID‐19.

The researchers concluded: “Our data supports the notion that diabetes should be considered as a risk factor for a rapid progression and bad prognosis of COVID‐19.

“More intensive attention should be paid to patients with diabetes, in case of rapid deterioration.More intensive attention should be paid to patients with diabetes, in case of rapid deterioration.”

To read the study in full, click here.

Picture credit: Shane

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